As a consultant, Giacomo has worked with clients from startups to law firms and Fortune 500 companies, as well as research groups at national laboratories and academic institutions. His consulting expertise spans these main subjects:

• optical design
• light scattering
• fluorescence
• microfluidics
• system design
• instrumentation development

The main application areas include:

• flow cytometry
• extracellular vesicles and exosomes
• hematology analysis
• cell analysis and sorting
• rare-event analysis
• in vitro diagnostics
• flame measurements and diagnostics

He founded Kinetic River Corp. in 2010 to provide design and product development services in the context of both life science research and clinical in vitro diagnostics (IVD). The projects Giacomo has undertaken at Kinetic River include:

• expert witness consulting
• design reviews
• technology and IP assessments
• optical component and system design
• custom flow cytometer design & development
• custom flame diagnostics design & development
• biophotonic instrumentation design & prototyping
• training and seminars on flow cytometry and biophotonics technology and markets

In addition, at Kinetic River he has developed eight flow cytometer products: the Delaware Flow NanoCytometer® (for extracellular vesicles), the Potomac (a modular flow cytometer), the Danube (a fluorescence lifetime flow cytometer), the Arno (a compensation-free flow cytometer), as well as standalone modules for fluidic control, flowcell monitoring, and signal amplification.

In 2013 he also co-founded BeamWise Inc., a company dedicated to the creation of design automation software tools for instrument designers and developers. The company was sold in 2023 to Design Power Inc.

Giacomo is an award-winning physicist and inventor with 27 years of experience in commercial R&D, several 510(k) product launches, 80 patents issued and 6 pending. He is a Senior Fellow of both SPIE and Optica. Prior to starting Kinetic River and BeamWise, he was Research Fellow, Senior Program Manager, and IP Manager at Abbott Hematology (part of the Diagnostics Division of Abbott Laboratories). Before that, he held various roles at Silicon Valley startups developing lasers for biomedical applications and optical waveguide devices for telecommunications, and worked on applied X-ray scattering research at Exxon. He received his Ph.D. in Applied Physics from Stanford University, and his B.A./M.A. in Physics from Harvard University.

Giacomo was a CNSV At-Large Director in 2015. He joined CNSV in 2011, and gave seminars at CNSV’s monthly meetings in 2012, 2014, 2017, and 2019.